Targeting Glycogen in Childhood Dementia with Expansion Potential to Larger Neurodegenerative Indications

Time: 1:03 pm
day: Pre-Conference Discussion Day

Details:

  • Childhood dementias such as Lafora Disease (LD) are fatal and fewer than 5% have effective treatments
  • An antibody-enzyme fusion clears accumulated pathogenic glycogen in the brain of LD animal models, rescuing metabolism and glycosylation patterns
  • Highlights a putative strategy for currently untreatable neurodegenerative diseases with demonstrated elevated glycogen

Speakers: